Protocol Update

Wishing all of you a very Merry Christmas!!

From: Edwin, sherry, Sherissa, Shaun & Chase

We had a consult with Dr. Freyer today. His 6-mp metabolite blood result came back good which surprised everybody. The result was for last month's 6-mp dose. For the past 2 weeks, his intake went from bad to worse. He does not like his bottle. So, only option now is to force orally. We are unsure of how much he is taking in especially the Methotrexate. We actually have called the clinic several times to ask what we need to do. We also met with the hospital psychologist this morning to see if they can help us with the situation. After the discussion, she knew how much we tried & will speak with Dr. Freyer before we meet him in the afternoon.

Right now, Dr. Freyer wants us to continue his current meds until Jan. 4 when he gets his LP. Chase will be taken out of the clinical trial. They will change the steroids & methotrexate to IV.

As for the daily 6-mp, we will continue to give orally & will check drug level again on the 4th before making any decisions.